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刘丽琴,女,北京科技大学化学与生物工程学院副教授。
人物简历
1、2012年7月-至今:美国新墨西哥大学药学院,博士后 2、2006年5月-至今:北京科技大学生物科学与工程系,副教授 3、2003年9月-2006年5月:中国协和医科大学北京协和医院, 博士后 4、2000年9月-2003年9月:理学博士,北京师范大学 5、1997年9月-2000年7月:理学硕士,东北林业大学 6、1993年9月-1997年7月:理学学士,东北林业大学
科研方向
社会职务
J Radioanal Nucl Chem审稿人
科研业绩
1、国家自然科学青年基金“叶酸受体靶向纳米脂质体硅纳米粒体系靶向投递缺氧诱导因子HIF-1 α siRNA 抗肿瘤活性的研究”,项目批准号:81301319,经费:23万元,时间:2014. 01- 2016.12,负责人; 2、中央高校基本科研业务费“新型核酸代谢类肿瘤早期诊断分子探针的研究”,项目编号:FRF-BR-12-017,经费:10万元,时间:2012.7-2014.7,负责人; 3、中俄国际合作项目“预防和免疫治疗疫苗及其新型佐剂增强功能的研究”,项目编号:2008AR, 经费:30 万
获得奖励
(1)王学斌,刘丽琴,陆洁,唐志刚,张现忠.二膦酸衍生物、99mTc标记的二膦酸衍生物及其应用,ZL 03156043.1,授权公告日2006年6月21日; (2)王学斌,刘丽琴,陆洁,唐志刚,张现忠.二膦酸衍生物、放射性99mTc标记的二膦酸衍生物及其应用,ZL 200310118032.3,授权公告日2007年3月14日。 获奖: (1)2010年9月8-11日在意大利Bressanone (Bolzano)举办的“the 8th International Symposium on TECHNETIUM and OTHER RADIOMETALS in CHEMISTRY and MEDICINE”会议上获得 “Marino Nicolini Prize”国际奖; (2)2011年4月获得化学与生物工程学院首届青年教师教学基本功大赛二等奖; (3)2012年9月获得北京科技大学先进工作者。
学术成果
论文论著
[1]Liqin Liu*, Manchen Zhao, Zhuo Wang, Yuanyan Qin, Xuebin Wang. Synthesis and biological evaluation of novel technetium-99mlabeled HYNIC-D-glucose as a potential tumor imaging agent. J Radioanal Nucl Chem, 2014, 301(4): 731–737;
[2]Liqin Liu*, Manchen Zhao, Zhuo Wang, Yuanyan Qin, Xuebin Wang. Synthesis and biodistribution of 99mTc-HYNIC-DG as a novel potential tumor imaging agent. Nuclear Medicine and Biology, 2014, 41(7): 623;
[3]Kubra Durkan, Zongrun Jiang, Tammy L Rold, Gary L Sieckman,Timothy J Hoffman, Rajendra Prasad Bandari, Ashley F Szczodroski, Liqin Liu, Yubin Miao, Tamila Stott Reynolds, Charles J Smith A heterodimeric [RGD-Glu-[(64)Cu-NO2A]-6-Ahx-RM2] αvβ3/GRPr-targeting antagonist radiotracer for PET imaging of prostate tumors. Nuclear Medicine and Biology, 2014, 41(2): 133-139;
[4]Liqin Liu, Yubin Miao*. Metastatic melanoma targeting property of a novel Tc-99m-labeled HYNIC-conjugated lactam bridge-cyclized alpha-MSH peptide. Nuclear Medicine and Biology. 2014, 41(7): 622;
[5]Liqin Liu*, Junwei Wang, Yaqian Wei, Manchen Zhao, Lirui Liu, Xuebin Wang. Synthesis and biodistribution of 99mTcN-thymidine dithiocarbamate as a potential tumor imaging agent. J Label Compd Radiopharm, 2013, 56: S347;
[6]Jianquan Yang, Liqin Liu, Yubin Miao*. Effects of the Arg-Pro and Gly-Gly-Nle Moieties on Melanocortin-1 Receptor Binding Affinities of α-MSH Peptides. ACS Medicinal Chemistry Letters 2013, 4(10): 1000-1004;
[7]Liqin Liu*, Junwei Wang, Yaqian Wei, Manchen Zhao, Lirui Liu, Xuebin Wang. Synthesis and biodistribution of a novel 99mTc complex of HYNIC-Conjugated thymidine as a potential tumor imaging agent. J Label Compd Radiopharm, 2013, 56: S348;
[8]Liqin Liu*, Guangrong Zhong, Yaqian Wei, Min Zhang, Xuebin Wang. Synthesis and biological evaluation of a novel 99mTc complex of HYNIC-conjugated aminomethylenediphos-phonate as a potential bone imaging agent. J Radioanal Nucl Chem, 2011, 288(2): 467-473;
[9]Liqin Liu*, Min Zhang, Guangrong Zhong, Xuebin Wang. Synthesis and biodistribution of a novel 99mTc complex of HYNIC-conjugated metronidazole as a potential tumor hypoxia imaging agent. J Radioanal Nucl Chem, 2011, 287(3): 847-852;
[10]Liqin Liu*, Guangrong Zhong, Min Zhang, Xuebin Wang. Preparation, characterization and biodistribution of new technetium-99m complexes with DMP-AMDP and DMP-ACPDP. Nuclear Medicine and Biology, 2010, 37(6): 703;
[11]Liqin Liu*, Guangrong Zhong, Min Zhang, Xuebin Wang. Preparation, characterization and biodistribution of 99mTc-HYNIC-ACPDP as a novel potential bone imaging agent. Nuclear Medicine and Biology, 2010, 37(6): 704;
[12]Liqin Liu*, Min Zhang, Guangrong Zhong, Xuebin Wang. Preparation, characterization and biodistribution of 99mTc-HYNIC-MN as a novel potential tumor hypoxia imaging agent. Nuclear Medicine and Biology, 2010, 37(6): 702.[1]