陈珣
人物简历
教育经历
[1]. 克莱姆森大学 生物工程 研究生 博士
[2]. 天津大学 生物医学工程 研究生 硕士
[3]. 天津大学 生物医学工程 本科 本科
工作经历
[1]. 北京航空航天大学 医学科学与工程学院 助理教授
[2]. 北京航空航天大学 生物与医学工程学院 博士后
研究方向
[1] 医用光子学、无标记分子成像、光学内窥镜、智能医学图像处理 1无标记分子成像 NADH/FAD分子自荧光成像用于细胞存活率研究; 脂质、蛋白、DNA分子相干拉曼散射成像用于肿瘤精准诊断; 2光学内窥镜 共聚焦消化内窥镜用于癌前病变筛查、肿瘤精准诊断; 自发拉曼、OCT内窥镜用于术中无创切缘检测;
科研项目
主持国家自然科学基金青年项目、北京市自然科学基金青年项目和小米联合项目、中国博士后基金面上项目等多项科研项目;同时参与多项科研项目,分别来自国家自然科学基金国家重大科研仪器项目,科技部重点研发计划等。
学术成果
1. Xun Chen, Zhouqiao Wu, Yexuan He, Zhe Hao, Qi Wang, Keji Zhou, Wanhui Zhou, Pu Wang, Fei Shan, Zhongwu Li, Jiafu Ji, Yubo Fan*, Ziyu Li*, Shuhua Yue*,Accurate and Rapid Detection of Peritoneal Metastasis from Gastric Cancer by AI-Assisted Stimulated Raman Molecular Cytology, Advanced Science, 2023, 00961.(期刊论文)
2. Chen, P.#, Chen, X.#, Hepfer, R.G., Damon, B.J., Shi, C., Yao, J.J., Coombs, M.C., Kern, M.J., Ye, T.* and Yao, H.*, 2021. A noninvasive fluorescence imaging-based platform measures 3D anisotropic extracellular diffusion. Nature communications, 12(1), pp.1-17.(期刊论文)
3. Chen, X., Li, Y., Wyman, N., Zhang, Z., Fan, H., Le, M., Gannon, S., Rose, C., Zhang, Z., Mercuri, J., Ye, T.* and Yao, H.*, 2021. Deep learning provides high accuracy in automated chondrocyte viability assessment in articular cartilage using nonlinear optical microscopy. Biomedical Optics Express, 12(5), pp.2759-2772.(期刊论文)
4. Chen, X., Cui, Sishan,Yan, Shuai,Zhang, Shuo, Fan, Yu, Gong,Yanqing, Zhou, Liqun, Wang, Ping,Yao, Lin*, Yue, Shuhua*, 2021. Hyperspectral stimulated Raman scattering microscopy facilitates differentiation of low-grade and high-grade human prostate cancer. Journal of Physics D Applied Physics, 54 (48), pp. 484001. (期刊论文)
5. Yang, Xuefang, Wang, Ye, Zhang, Hejun, Qin, Haoye, Wang, Siyu, Tong, Yihang, Zhou, Keji,Sun, Rui, Yue, Shuhua*, Chen, X. *, Ding,Shigang*, Wang,Pu*, 2022. Fiber-optic large-depth 3D chromatic confocal endomicroscopy, Biomedical Optics Express, 13(1): 300-313(期刊论文)
6.Jia, H; Liu, J; Fang, TH; Zhou, Z; Li, R.; Yin, WZ; Qian, Y; Wang, Q; Zhou, W.; Liu, C; Sun, D.; Chen, X; Ouyang, Z; Dong, J.; Wang, Y.; Yue, S., 2023. The role of altered lipid composition and distribution in liver fibrosis revealed by multimodal nonlinear optical microscopy, Science Advances, 9(2):12(期刊论文)
7. Richards, D.J., Li, Y., Kerr, C.M., Yao, J., Beeson, G.C., Coyle, R.C., Chen, X., Jia, J., Damon, B., Wilson, R. and Hazard, E.S., 2020. Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity. Nature biomedical engineering, 4(4), pp.446-462. (期刊论文)
8. Yan, W., Yang, Y., Tan, Y., Chen, X., Li, Y., Qu, J.* and Ye, T.*, 2017. Coherent optical adaptive technique improves the spatial resolution of STED microscopy in thick samples. Photonics research, 5(3), pp.176-181. (期刊论文)
9. Chen, X., Feng, Y., Lu, J.Q., Liang, X., Ding, J., Du, Y. and Hu, X.H.*, 2013. Fast method for inverse determination of optical parameters from two measured signals. Optics letters, 38(12), pp.2095-2097. (期刊论文)
10. Li, Y., Chen, X., Watkins, B., Saini, N., Gannon, S., Nadeau, E., Reeves, R., Gao, B., Pelligrini, V., Yao, H.* and Mercuri, J.*, 2020. Nonlabeling and quantitative assessment of chondrocyte viability in articular cartilage with intrinsic nonlinear optical signatures. Experimental Biology and Medicine, 245(4), pp.348-359.(期刊论文)
11. Tian, P., Chen, X., Jin, J., Lu, J.Q., Liang, X. and Hu, X.H.*, 2018. Stochastic model for quantifying effect of surface roughness on light reflection by diffuse reflectance standards. Optical Engineering, 57(9), p.094104.(期刊论文)[1]