魏勋斌

魏勋斌，美国University of California, Irvine生物物理学博士/上海交通大学MED-X研究院、生物医学工程学院特聘教授 .

魏勋斌
原图链接 来自分析测试百科网 美国科学院院士
原文名	Xunbin Wei
国籍	中国
职业	特聘教授

1999年获得Howard Hughes(霍华得休斯)基金在哈佛大学医学院David Clapham教授(美国科学院院士)的实验室从事博士后研究。2001年起在哈佛大学医学院担任讲师职务并从事科学研究。现为美国生物物理学会和美国光学生物医学工程学会会员。

目录

人物简介

美国University of California, Irvine生物物理学博士/上海交通大学MED-X研究院、生物医学工程学院特聘教授

人物生平

长期从事生物医学光子学的研究与应用，已发表30余篇高质量学术论文(包括Nature, PNAS)和取得研究专利结果7项。主要研究方面有: 1)生物医学光学影像技术及其在癌症扩散和干细胞方面的研究。实验室正在建设的一种新的生物医学光学仪器"活体流式细胞仪", 将无须抽血即可实时检测活体小动物(如实验用的

老鼠)循环系统内某个(某些)细胞群体(如CD4+白细胞)的存在并可以进行定量分析与监测，适用于实验室对癌症细胞的扩散研究、药物的早期筛选、血细胞和白细胞的免疫分析等; 2)激光生物医学光子学在医学临床上的研究和实际应用，如无创检测皮肤疾病和治疗，老年痴呆症和帕金森症的早期光学诊断和早期治疗等;3)运用活体的光学分子影像技术及新的纳米技术进行药物吸收(Drug Delivery)的研究。

代表论文

• Wang L, Fan Z, Zhang J, Changyi Y, Huang C, Gu Y, Xu Z, Tang Z, Lu W, Wei X, Li C.Evaluating tumor metastatic potential by imaging intratumoral acidosis via pH-activatable near-infrared fluorescent probe. Int J Cancer. 2014 Epub. (corresponding author; impact factor: 6.2)
• Zhang Y, Cai W, Huang Q, Gu Y, Shi Y, Huang J, Zhao F, Liu Q, Wei X, Jin M, Wu C, Xie Q, Zhang Y, Wan B, Zhang Y. Mesenchymal stem cells alleviate bacteria-induced liver injury in mice by inducing regulatory dendritic cells. Hepatology. 2014, 59(2):671-82. (impact factor: 11.19)
• Zhong MC, Wei XB, Zhou JH, Wang ZQ, Li YM. Trapping red blood cells in living animals using optical tweezers. Nat Commun. 2013,4:1768. (corresponding author; impact factor: 10.7)
• Liao Y, Cheng Y, Liu C, Song J, He F, Shen Y, Chen D, Xu Z, Fan Z, Wei X, Sugioka K, Midorikawa K. Direct laser writing of sub-50 nm nanofluidic channels buried in glass for three-dimensional micro-nanofluidic integration. Lab Chip. 2013, 13(8):1626-31. (impact factor: 5.8)
• Fan ZC, Yan J, Liu GD, Tan XY, Weng XF, Wu WZ, Zhou J, Wei XB. Real-time monitoring of rare circulating hepatocellular carcinoma cells in an orthotopic model by in vivo flow cytometry assesses resection on metastasis. Cancer Res. 2012, 72(10):2683-91. (corresponding author; impact factor: 9.3)
• Wang L, Zhu X, Xie C, Ding N, Weng X, Lu W, Wei X, Li C. Imaging acidosis in tumors using a pH-activated near-infrared fluorescence probe. Chem Commun (Camb). 2012, 11;48(95):11677-9. (corresponding author; impact factor: 6.7)
• Yan H, Wang L, Wang J, Weng X, Lei H, Wang X, Jiang L, Zhu J, Lu W, Wei X, Li C. Two-order targeted brain tumor imaging by using an optical/paramagnetic nanoprobe across the blood brain barrier. ACS Nano. 2012, 24;6(1):410-20. (corresponding author; impact factor: 12.0)
• Hu L, Fan Z, Du H, Ni R, Zhang S, Yin K, Ye J, Zhang Y, Wei X, Zhang X, Gross PL, Kunapuli SP, Ding Z. BF061, a novel antiplatelet and antithrombotic agent targeting P2Y₁₂ receptor and phosphodiesterase. Thromb Haemost. 2011, 106(6):1203-14. (impact factor: 5.8)
• Li C, Li K, Yan H, Li G, Xia J, Wei X. Dextran based pH-activated near-infrared fluorescence nanoprobe imaging the acidic compartments in cancer cells. Chem Commun (Camb). 2010, 46(8):1326-8. (corresponding author; impact factor: 6.7)
• Sipkins DA, Wei X, Wu JW, Runnels JM, Cote D, Means TK, Luster AD, Scadden DT, Lin CP. In vivo imaging of specialized bone marrow endothelial microdomains for tumor engraftment. Nature. 2005, 435:969-73. (impact factor: 42.4).
• Georgakoudi I, Solban N, Novak J, Rice, W, Wei X, Hasan, T, Lin CP. In vivo flow cytometry: A new method for enumerating circulating cancer cells. Cancer Research. 2004, 64:5044-7 (impact factor: 9.3).
• Kunstfeld R, Hirakawa S, Hong YK, Lin, CP, Wei X, Bohlen P, Detmar. Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. Blood. 2004, 104:1048-57 (impact factor: 9.8).
• Wei X, Tromberg BJ, Cahalan MD. Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling. Proc Natl Acad Sci U S A. 1999, 96(15):8471-6.(impact factor: 9.8).