李焕改查看源代码讨论查看历史
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李焕改,女,北京科技大学化学与生物工程学院讲师。
人物简历
2003.09-2007.07:中国矿业大学,工学学士,专业:生物工程
2007.09-2010.07:大连理工大学,理学硕士,专业:生物化学与分子生物学
2012.04-2015.03: 日本东京大学,农学博士,专业:生产与环境生物学
2015.04-2015.09:日本东京大学亚洲生物资源与环境中心,特任研究员、特任助理教授
2015.12-2021.10:清华大学生命科学学院,博士后
2022.01-至今:北京科技大学化学与生物工程学院,讲师
科研方向
病毒与宿主植物玉米的互作,玉米抗病毒基因的克隆、鉴定及分子育种,玉米营养品质的遗传研究
科研业绩
已主持或主要参与完成国家自然科学基金1项,在研1项。
1. 国家自然科学基金国际(地区)合作与交流项目:木尔坦棉花曲叶病毒致病机理研究,2020.01-2024.12,264万元,在研,主要参与人
2.国家自然科学基金青年科学基金项目:木尔坦棉花曲叶病毒 C4 蛋白抑制转录基因沉 默的机理研究,2018.01-2018.12,10万元,已结题,主持
学术成果
论文论著
(#equal contribution; * corresponding author)
1. Li, H.#, Zhang, D.#, Xie, K., Wang, Y., Liao, Q., Hong, Y., and Liu, Y.* (2021). Efficient and high-throughput pseudorecombinant-chimeric Cucumber mosaic virus-based VIGS in maize. Plant Physiology 187, 2865-2876.
2. Wang, Y.#, Gong, Q.#, Wu, Y., Huang, F., Ismayil, A., Zhang, D., Li, H., Gu, H., Ludman, M., Fátyol, K., Qi, Y., Yoshioka, K., Hanley-Bowdoin, L., Hong, Y., and Liu, Y.* (2021). A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants. Cell Host & Microbe 29, 1393-1406.e1397.
3. Xu, X.J.#, Li, H.G.#, Cheng, D.J., Liu, L.Z., Geng, C., Tian, Y.P., and Li, X.D.* (2020). A Spontaneous Complementary Mutation Restores the RNA Silencing Suppression Activity of HC-Pro and the Virulence of Sugarcane Mosaic Virus. Frontiers in Plant Science 11, 1279.
4. Ismayil, A.#, Haxim, Y.#, Wang, Y., Li, H., Qian, L., Han, T., Chen, T., Jia, Q., Yihao Liu, A., Zhu, S., Deng, H., Gorovits, R., Hong, Y., Hanley-Bowdoin, L., and Liu, Y.* (2018). Cotton Leaf Curl Multan virus C4 protein suppresses both transcriptional and post-transcriptional gene silencing by interacting with SAM synthetase. PLoS Pathogens 14, e1007282.
5. Liu, N.#, Xie, K.#, Jia, Q.#, Zhao, J., Chen, T., Li, H., Wei, X., Diao, X., Hong, Y., and Liu, Y.* (2016). Foxtail Mosaic Virus-Induced Gene Silencing in Monocot Plants. Plant Physiology 171, 1801-1807.
6. Li, H.*, Kondo, H., Kühne, T., and Shirako, Y*. (2016). Barley Yellow Mosaic Virus VPg Is the Determinant Protein for Breaking eIF4E-Mediated Recessive Resistance in Barley Plants. Frontiers in Plant Science 7, 1449.
7. Li, H., and Shirako, Y*. (2015). Association of VPg and eIF4E in the host tropism at the cellular level of Barley yellow mosaic virus and Wheat yellow mosaic virus in the genus Bymovirus. Virology 476, 159-167.
8. Xu, P., Li, H.*, Liu, J., Luan, Y., Yin, Y., and Bai, J. (2011). Sequence and structure prediction of RNA-dependent RNA polymerase of lily symptomless virus isolated from L. × 'Casablanca'. Archives of Virology 156, 939-943.[1]