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叢 馨檢視原始碼討論檢視歷史

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叢 馨
北京大學基礎醫學院

叢 馨,女,北京大學基礎醫學院生理學與病理生理學系副教授。

人物履歷

2007年7月於北京大學獲醫學學士學位;2012年7月於北京大學基礎醫學院病理生理學專業獲醫學博士學位;2012年7月至2014年7月於北京大學醫學部神科所從事博士後工作。

研究領域

從事細胞間緊密連接蛋白在唾液腺上皮血管內皮中的功能研究。

主持國自然青年和面上項目共3項,北京市自然基金2項,國家博士後面上基金1項,參加國自然重大項目1項;

科研項目

首批中國科協「青年人才托舉工程」入選者,獲得2015年教育部科技進步二等獎和2016年華夏醫學獎一等獎(均第5完成人)、2016年國際生理學大會青年優秀論文報告會一等獎、2015年全國唾液腺疾病學術研討會優秀論文一等獎、2015年第十屆中國病理生理學會全國代表大會優秀論文二等獎等。

學術成果

論文

1. Zhu M*, Min S, Mao X, Zhou Y, Zhang Y, Li W, Li L, Wu L, Cong X#, Yu G#. Interleukin-13 promotes cellular senescence through inducing mitochondrial dysfunction in IgG4-related sialadenitis. Int J Oral Sci . (in publication)

2. Li Z*, Cong X#, Kong W#. Matricellular proteins: potential biomarkers and mechanistic factors in aortic aneurysms. J Mol Cell Cardiol . 2022, 169: 41-56. Review

3. Mao X*, Min S, He Q#, Cong X#. In vivo vascular permeability assessment in mouse submandibular gland. J Vis Exp . (in publication)

4. Min SN*, Zhu MQ, Mao XD, Li W, Wei T, Mei M, Zhang Y, Wu LL, Yu GY#, Cong X#. Contribution of interleukin-4-induced epithelial cell senescence to glandular fibrosis in IgG4-related sialadenitis. Arthritis Rheumatol . 2022, 74(6): 1070-1082.

5. Min SN*, Wu LL, Zhang YY, Zhu WX, Cong X#, Yu GY#. Disruption of tight junction structure contributes to secretory dysfunction in IgG4-related sialadenitis. J Mol Histol . 2020, 51(1): 33-46.

6. Yang NY*, Ding C, Li J, Zhang Y, Xiang RL, Wu LL, Yu GY, Cong X#. Muscarinic acetylcholine receptor-mediated tight junction opening is involved in epiphora in late phase of submandibular gland transplantation. J Mol Histol . 2017, 48(2): 99-111.

7. Cong X*, Kong W#. Endothelial tight junctions and their regulatory signaling pathways in vascular homeostasis and disease. Cell Signal . 2020, 66: 109485. (IF 4.315) Review

8. Min SN*, Cong X*, Zhang Y, Xiang RL, Zhou Y, Yu GY#, Wu LL#. Tricellulin modulates transport of macromolecules in the salivary gland. J Dent Res . 2020, 99(3): 302-310.

9. Cong X*, Zhang XM, Zhang Y, Wei T, He QH, Zhang LW, Hua H, Lee SW, Park K, Yu GY#, Wu LL#. Disruption of endothelial barrier function is linked with hyposecretion and lymphocytic infiltration in salivary glands of Sjögren's syndrome. Biochim Biophys Acta Mol Basis Dis . 2018, 1864(10): 3154-3163.

10. Ding C*, Cong X*, Zhang XM, Li SL, Wu LL#, Yu GY#. Decreased interaction between ZO-1 and occludin is involved in alteration of tight junction in transplanted epiphora submandibular glands. J Mol Hist. 2017, 48(3): 225-234.

11. Qi W*, Cong X*, Zhang XM, Wang ZY, Yang NY, Ding C, Shan XF, Wu LL, Yu GY#. Parasympathectomy increases resting salivary secretion in normal and irradiated submandibular glands of rats. Eur J Oral Sci . 2017, 125(2): 110-118.

12. Cong X*, Zhang Y, He QH, Wei T, Zhang XM, Zhang JZ, Xiang RL, Yu GY#, Wu LL#. Endothelial tight junctions are opened in cholinergic-evoked salivation in vivo . J Dent Res . 2017, 96(5): 562-570. Cover image

13. Zhang LW*, Cong X*, Zhang Y, Wei T, Su YC, Serrão AC, Brito AR Jr, Yu GY, Hua H#, Wu LL#. Interleukin-17 impairs salivary tight junction integrity in Sjögren's syndrome. J Dent Res . 2016, 95(7): 784-792.

14. Cong X*, Zhang Y, Li J, Mei M, Ding C, Xiang RL, Zhang LW, Wang Y, Wu LL#, Yu GY#. Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells. J Cell Sci . 2015, 128(12): 2271-2286.

[Highlighted article並獲得F1000Prime機構評選的F1000文章推薦(Reviewed by Faculty of 1000.

15. Cong X*, Zhang Y, Yang NY, Li J, Ding C, Ding QW, Su YC, Mei M, Guo XH, Wu LL#, Yu GY#. Occludin is required for TRPV1-modulated paracellular permeability in the submandibular gland. J Cell Sci . 2013, 126(Pt5): 1109-1121.

16. Cong X*, Zhang Y*, Shi L, Yang NY, Ding C, Li J, Ding QW, Su YC, Xiang RL, Wu LL#, Yu GY#. Activation of transient receptor potential vanilloid subtype 1 increases expression and permeability of tight junction in normal and hyposecretory submandibular gland. Lab Invest . 2012, 92(5): 753-768.

17. Zhang Y*, Cong X*, Shi L, Xiang B, Li YM, Ding QW, Ding C, Wu LL#, Yu GY. Activation of transient receptor potential vanilloid subtype 1 increase secretion of the hypofunctional, transplanted submandibular gland. Am J Physiol Gastrointest Liver Physiol . 2010, 299(1): G54-G62.[1]

參考資料