王柳
人物事迹
2001年毕业于中国农业科学院研究生院,获农学博士学位;
2001年进入北京大学博士后流动站;
自2003年中国科学院动物研究所副研究员。主要从事发育生物学和细胞生物学研究。[2]
主要研究方向为:
细胞核移植及重编程的分子机制、干细胞和治疗性克隆。[3]
课题成果
1991年起主持和参加了国家“863”项目、国家重点基础研究发展规划(973)项目、国家自然科学基金、“八五”农业部重点项目、“九五”农业部重点项目等10余个项目的研究工作;[4]
发表论文30余篇;获黑龙江省科技进步一等奖1项、哈尔滨市科技进步二等奖1项。
研究领域
从事动物克隆、胚胎干细胞培养、重编程的分子机制研究。[5]
代表论著
Yang Yu, Jindao Wu, Yong Fan, Zhuo Lv, Xuejiang Guo, Chun Zhao, Rong Zhou, Zhuo Zhang, Fuqiang Wang, Min Xiao, Ling Chen, Hui Zhu, Wen Chen, Min Lin, Jiayin Liu, Zuomin Zhou, Liu Wang, Ran Huo, Qi Zhou*, Jiahao Sha. Evaluation of blastomere biopsy using mouse model indicates the potential high-risk of neurodegenerative disorders in the offspring. Mol Cell Proteomics. 2009 Mar 11. [Epub ahead of print]
Minyue Ma, Xuejiang Guo, Fuqiang Wang, Chun Zhao, Zichuan Liu, Zhonghua Shi, Yufeng Wang,Ping Zhang, Kemei Zhang, Ningling Wang, Min Lin, Zuomin Zhou, Jiayin Liu, Qingzhang Li, Liu Wang, Ran Huo, Jiahao Sha,and Qi Zhou*. Protein Expression Profile of the Mouse Metaphase-II Oocyte. J Proteome Res. 2008; 7(11): 4821-4830.
Qingyun Mai, Yang Yu, Tao Li, Liu Wang, Mei-jue Chen, Shu-zhen Huang, Canquan Zhou, Qi Zhou*. Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. Cell Research. 2007; 17:1008-1019.
Yu Y, Ding C, Wang E, Chen X, Li X, Zhao C, Fan Y, Wang L, Beaujean N, Zhou Q, Jouneau A, Ji W. Piezo-assisted nuclear transfer affects cloning efficiency and may cause apoptosis. Reproduction. 2007 May;133(5):947-54.
Yang J, Yang S, Beaujean N, Niu Y, He X, Xie Y, Tang X, Wang L, Zhou Q*, Ji W*. Epigenetic marks in cloned rhesus monkey embryos: comparison with counterparts produced in vitro. Biol Reprod. 2007 76(1):36-42.
Zhao C, Yao R, Hao J, Ding C, Fan Y, Dai X, Li W, Hai T, Liu Z, Yu Y, Wang Y, Hou X, Ji W, Zhou Q, Jouneau A, Zeng F, Wang L*. Establishment of customized mouse stem cell lines by sequential nuclear transfer. Cell Res. 2007 Jan;17(1):80-7.
Wang ErYao, YU Yang, Li XueMei, JIAO LiHong, Wang Liu* Effects of different nuclear transfer and activation methods on the development of mouse somatic cell cloned embryos Chinese Science Bulletin. 2007, 52 (1) :1-6
Tianqing Li, Shufen Wang, Yunhua Xie, Yongqing Lu, Xiuzhen Zhang, Liu Wang, Shihua Yang, Don Wolf, Qi Zhou* and Weizhi Ji*,Transplantable neural progenitor populations derived from rhesus monkey embryonic stem cells.Stem Cells. 2005 Oct;23(9):1295-303. Epub 2005 Jul 28
Tianqing Li, Shufen Wang, Yunhua Xie, Yongqing Lu, Xiuzhen Zhang, Liu Wang, Shihua Yang, Don Wolf, Qi Zhou* and Weizhi Ji*, Homologous feeder cells support undifferentiated growth and pluripotency in monkey embryonic stem cells. Stem Cells. 2005 Sep;23(8):1192-9. Epub 2005 Jun 13
Wang L, Zheng A, Yi L, Xu C, Ding M, Deng H. Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins. Biochem Biophys Res Commun. 2004, 325(1): 302-7
L.Wang, G.Z.Tong, H.Q.Liu, Z.B.Yang, H.J.Qiu, X.G.Kong, M.Wang., Proviral Genomic Sequence Analysis of Chinese Donkey Leukocyte Attenuated Equine Infectious Anemia Virus Vaccine and its Parental Virus Strain Liaoning. Science in China. Series C-life sciences, 2002, 45(1): 57-67.[6]