劉貝檢視原始碼討論檢視歷史
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劉貝，男，北京大學未來技術學院教授。
人物履歷
教育背景
2005-2009 華中科技大學，生物醫學工程本科
2009-2014 華中科技大學，中科院生物物理研究所 博士 （導師：徐濤院士）
工作簡歷
2015.1 – 2019.4 北卡羅萊納大學教堂山分校，博士後
2019.5 – 2022.4 北卡羅萊納大學教堂山分校，研究助理教授
2022.4 – 北京大學未來技術學院，助理教授
研究方向
為分子活性成像探針及光遺傳學工具的設計與應用。並通過多學科交叉，涵蓋蛋白質工程、顯微成像系統以及深度學習等多個新興領域。
學術成果
論文
1. Liu, B.*, Stone, O.*, Pablo, M.*, et al. Biosensors based on peptide exposure show single molecule conformations in live cells. Cell. 184(22):5670-5685.e23. doi: 10.1016/j.cell.2021.09.026 (2021).
2. Jin, L.*, Liu, B.*, #, Zhao, F., et al. Deep learning enables structured illumination microscopy with low light levels and enhanced speed. Nat Commu. 11, 1934 (2020)
3. Liu, B., Marston, D.J., Hahn, K.M. Engineering Optogenetic Protein Analogs. Methods Mol Biol. 2173: 113-126 (2020). (book chapter)
4. Stone, O.*, Kaul, N.*, Liu, B.*, et al. Optogenetic control of Cofilin and αTAT in living cells using Z-lock. Nat Chem Biol 15, 1183–1190 (2019).
5. Liu, B.*, Hobson, C.*, et al. VIEW-MOD: a versatile illumination engine with a modular optical design for fluorescence microscopy. Opt. Express 27, 19950-19972 (2019)
6. Liu, B.*, Xue, Y.*, Zhao, W.*, et al. Three-dimensional super-resolution protein localization correlated with vitrified cellular context. [J]. Scientific reports, 2015, 5.
7. Chen, S.*, Li, L.*, Li, J.*, Liu, B., et al. SEC-10 and RAB-10 coordinate basolateral recycling of clathrin-independent cargo through endosomal tubules in Caenorhabditis elegans [J]. Proc Natl Acad Sci USA, 2014, 111(43): 15432-15437.
8. Chang, H.*, Zhang, M.*, Ji, W.*, Chen, J., Zhang, Y., Liu, B., Lu, J., Zhang, J., Xu, P., and Xu, T. (2012). A unique series of reversibly switchable fluorescent proteins with beneficial properties for various applications. Proc Natl Acad Sci USA.
9. Zhang, M.*, Chang, H.*, Zhang, Y.*, Yu, J., Wu, L., Ji, W., Chen, J., Liu, B., Lu, J., Liu, Y., Zhang, J., Xu, P. and Xu, T. (2012). Rational design of true monomeric and bright photoconvertible fluorescent proteins. Nature Methods.[1]