尹昊琰檢視原始碼討論檢視歷史
尹昊琰，男，合肥工業大學化學與化工學院講師。
人物履歷
2011年9月–2015年7月，北京大學 化學與分子工程學院 化學專業學習，獲學士學位；
2015年9月–2021年6月，北京大學 化學與分子工程學院無機化學專業學習，碩博連讀，獲博士學位；
2021年12月–至今，合肥工業大學 化學與化工學院，講師。
研究領域
基於金屬配合物的新型小分子熒光探針和金屬藥物的設計合成、性質及機制研究以及探索它們在生物醫學領域的應用和臨床轉化
研究成果
圍繞新型小分子金屬配合物熒光探針和金屬藥物進行研究，近年來已在包括Angew. Chem. Int. Ed., Chem. Sci., Chem. Commun., Eur. J. Inorg. Chem.在內的國際重要學術期刊上發表SCI學術論文十餘篇。
專利
1. Junlong Zhang, Haoyan Yin, Bingwu Wang, Main-group metal complex with cancer cell killing ability and preparation and application thereof, 2019, Patent WO 2019214691
學術成果
1. Hao-Yan Yin+, Jiu-Jiao Gao+, Xuemin Chen+, Bin Ma+, Zi-Shu Yang, Juan Tang, Bing-Wu Wang, Tianfeng Chen, Chu Wang, Song Gao, Jun-Long Zhang*, A Gallium(III) Complex that Engages Protein Disulfide Isomerase A3 (PDIA3) as an Anticancer Target, Angew. Chem. Int. Ed., 2020, 59, 20147-20153 (+: These authors contributed equally to this work).
2. Hao-Yan Yin, Jing Lai, Juan Tang, Yanli Shang*, and Jun-Long Zhang*, A cryptand-type aluminum tris(salophen) complex: synthesis, characterization, and cell imaging application, Inorganics, 2018, 6, 20;
3. Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Sulfur speciation defined subcellular localization of coumarin derivatives: Correlation of structural relationship to biological behaviors, Chin. Chem. Lett., 2018, 29, 267-270.
4. Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Luminescent metal salen complex as intracellular microviscosity fluorescent sensor, Sci. Sin. Chim., 2017, 47, 267.
5. Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Introducing Metallosalens to Biological Studies: The Renaissance of Traditional Coordination Complexes, Eur. J. Inorg. Chem., 2017, 44, 5085-5093.
6. Juan Tang, Hao-Yan Yin and Jun-Long Zhang*, A luminescent aluminium salen complex allows for monitoring dynamic vesicle trafficking from the Golgi apparatus to lysosomes in living cells, Chem. Sci., 2018, 9, 1931-1939.
7. Juan Tang, Hao-Yan Yin and Jun-Long Zhang*, Luminescent Zinc Complexes as Bioprobes for Imaging Molecular Events in Live Cells, Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells, Elsevier press, 2017.[1]